A group of Antwerp painters, including Pieter Neefs I, emerged in the 1580s. They used a clear geometric perspective to depict the space of the interiors realistically. Their works effectively reproduced the depth of the nave space, shown from a slightly elevated vantage point. "The Interior of the Antwerp Cathedral" is one of Neefs' many paintings representing the interior of the Antwerp Cathedral. Those artworks are very similar and differ only in the staffage and individual details of the decor. The Lviv painting shows a perspective view from the main entrance side. There are some figures in the cathedral in the foreground. Little further is a crowd of people listening to the priest's mass in front of the pulpit. Some figures, such as beggars or a woman giving an offering, attract special attention. They most likely emphasise the importance of offering as a Christian virtue. Frans Francken II, who frequently cooperated with Pieter Neefs I, created the figures in the work.